The study of single-top-quark production has required the development of new insights into every aspect of QCD: from the composition of the proton, to the subtle nature of inclusive versus exclusive measurements, to a general reinterpretation of the connection between theoretical calculations and experimental observables. After a brief review of why t-channel single top plays the modern role of deep inelastic scattering in physics at hadron colliders, I will explain how s-channel single top plays the role of a new Drell Yan. In particular, I will describe recent model-independent searches for new charged vector currents (W-prime bosons) and their implications for theory and experiment.