Positron emission mammography (PEM) is a technique to obtain planar images of the breast for detection of potentially cancerous, radiotracer-avid tumors. To increast the diagnostic accuracy of this method, use of minimally invasive methods (e.g., core biopsy) may be desirable for obtaining tissue samples from lesions detected with PEM. The purpose of this study was to test the capabilities of a novel method for performing PEM-guided stereotactic breast biopsies.

Authors thank Bryan Smith of the radiochemistry section of the Center for Advanced Imaging at West Virginia University for supplying the radionuclides used in this study and Lorie McCue of the Betty Puskar Breast Care Center of West Virginia University for acquiring the x-ray mammograms. This study was supported in part by a grant from West Virginia University and grant 1 R21 CA82752-01 from the National Cancer Institute and by U.S. DOE under contract DE-AC05-84ER40150.

Authors: Raymond R. Raylman, Stan Majewski, Randy Wojcik, Andrew G. Weisenberger, Brian Kross, Vladmir Popov, Judith S. Schreiman, Harry A. Bishop

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