Estimate of Two-Photon Exchange in Elastic Electron-Proton Scattering: QCD factorisation approach Nikolai Kivel Ruhr University, Bochum, Germany and Petersburg NPI, Russia We estimate the TPE exchange contribution to elastic electron-proton scattering at large momentum transfer Q^2 using QCD factorisation approach. Using several models for the nucleon distribution amplitudes, we provide estimates for existing data and ongoing experiments.