In this talk, I will present a development of a gamma-ray vortex using an inverse Compton scattering (ICS). The vortex beam forms a helical wavefront along the direction of propagation and carries discrete values m hbar of orbital angular momentum (OAM) per photon. Fundamental and applied research on optical vortices using visible wavelength lasers is ongoing. However, vortex beams are not limited to visible light but include the sub-MeV electron vortex, ~ 10 keV X-ray vortex, terahertz wave vortex, and cold neutron vortex. ICS of a laser photon by a relativistic electron is one of the promising technique to generate the gamma-ray vortex in the MeV and GeV range. Gamma-ray vortex providing an additional degree of freedom will open new research opportunities to the nuclear physics. Characteristics of the gamma-ray vortices generated via two different ICS methods and basic experiments of the optical vortex laser generated by a holographic grating will be presented.